A high ankle sprain involves injury to the syndesmotic ligaments, which stabilise the tibia (shinbone) and fibula (the smaller bone alongside it) above the ankle joint. These ligaments are strong connective tissues that help maintain ankle alignment during movement. The syndesmosis is made up of several key structures, including the anterior inferior tibiofibular ligament (AITFL), posterior inferior tibiofibular ligament (PITFL), and the interosseous membrane. Damage to these structures may compromise ankle stability.
This type of injury differs from a common lateral ankle sprain, which affects the ligaments on the outer side of the ankle. High ankle sprains often occur during sports activities and are commonly associated with rotational forces combined with ankle dorsiflexion. Because these violent twisting motions travel up the leg, athletes should also be mindful of concurrent knee injuries, and may need to seek ACL tear treatment if they experience a popping sensation or instability further up the leg.